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Bella Baxter (Emma Stone) is a revived pregnant suicide victim by mad genius doctor Godwin Baxter (Willem Defoe), who swaps her fetus's brain with the dead woman's. Therefore, Bella has an unencumbered infant's mind that slowly will need to learn the way of things in life. Godwin assigns his good natured pupil McCandles (Ramy Youssef) to look after Baxter and soon the young man is smitten by Bella's beauty and her total lack of social ettiquettes. Fearing her being taken advantage by the rotten world outside the confines of his castle, Godwin makes McCandles Bella's betrothed. As soon as she grows and learn sexual pleasures, she is prayed on by shyster playboy Duncun Wedderburn (Mark Ruffalo) and leaves the country in a sensual whirlwind trip across Europe and North Africa. There Bella learns that physical pleasure is not all there is to be in the world, but pain, pain of others and injustices also exist.
The heightened sense of Victorian imagination, in the hands of Lanthimos, the turn of the century Europe - From Lisbon and Athens to Paris and Alexandria are colorful and whimsical in that bizaare early Czech animation (ie. Karel Zeman) way. Bella learns the world's injustices and unfairness first-hand and determines her destiny every step of the way herself while keeping her always sunny and curious disposition. It might be a naive notion to think that our super complicated 21st century society is just a construct that the past doesn't hold any influence over our lives, that human beings start as a blank page and free to self determine the future. But it's a nice thought.